Oleate and palmitoleate are major components of membrane phospholipids cholesterol esters and alkyl diacylglycerol in humans the enzyme is encoded by the scd gene stearoyl coa desaturase 1 is a key enzyme in fatty acid metabolism it is responsible for forming a double bond in stearoyl coa. Stearoyl coenzyme a desaturase 1 is a 9 fatty acid desaturase that catalyzes the synthesis of monounsaturated fatty acids and has emerged as a key regulator of metabolism suggesting that central nutrient sensing also regulates hepatic lipid metabolism dobrzyn a man wc et al stearoyl coa desaturase 1 gene expression is necessary . James ntambi has gathered top authors to write about the remarkable growth of research on the role of the stearoyl coa desaturase scd genes in metabolism in different species including human. First book to focus on scd genes in lipid metabolism this book includes chapters by leading researchers on scd genes in the brain heart muscle liver metabolism colitis and more gives an overview of the growth of research on the role of the stearoyl coa desaturase scd genes in metabolism . Get this from a library stearoyl coa desaturase genes in lipid metabolism james m ntambi obesity and diabetes develop as a complex result of genetic metabolic and environmental factors and are characterized by increased lipogenesis and lipid accumulation in many tissues stearoyl coa
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